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KRAS Mutation
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KRAS Mutation- clarientinc.com
V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog also known as KRAS is a protein which in humans is encoded by the KRAS gene. KRAS has been extensively studied in a wide array of human malignancies, including mCRC. Mutant KRAS can be detected in approximately 30-50% of colorectal cancers. The Ras-Raf-MAPK pathway lies just downstream of EGFR.
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